There's a lot of noise in the supplement world about what to take to
feel or look younger. We've combed through the research to share the five
supplements that have the most promising research behind them for their
Need to Know About EGCG
Lets spill the tea on EGCG. Epigallocatechin gallate (or EGCG) is a type of catechin that is found
in many teas and is known for its antioxidant and anti-inflammatory effects, as
well as a wide range of health benefits!
EGCG is found in varying concentrations in many
teas, but is found mostly in green tea. Other teas like oolong and black teas
are partially or fully oxidized, so they have much lower concentrations of
EGCG. If you're somewhat of a tea connoisseur, you'll know that tea can vary
from region to region, whether it is grown in shade versus sun, and even differ
depending on what season the tea is harvested in. Research has shown that
Japanese steamed teas have higher catechin concentrations. Tea from the second
harvest is usually higher in EGCG versus the first harvest as well. On the tea
plant itself, the younger plant leaves toward the top have more EGCG over the
mature leaves on the lower part of the plant.
EGCG is great for heart health by decreasing
inflammation and reducing blood pressure. Studies have also shown that EGCG can
protect brain cells from oxidative stress and increase brain function. This
helps to improve task performance and display improved memory recall.
Additionally, the green tea rich in EGCG and caffeine have been linked to
assistance of weight loss through balancing hormones that regulate
thermogenesis, which is how your body burns calories to produce energy/heat.
Individuals with skin issues like dermatitis and rosacea have been known to
show improvement with EGCG as well. Topical green tea extract can help with
skin elasticity, inflammation and other signs of aging.
Taking EGCG can also help to reduce liver
enzyme levels through reduction of inflammation and oxidative stress. However,
excessive intake of EGCG has been linked to increased risk of liver damage, so
you should always consult with your doctor if you plan on taking any
supplements with EGCG, or consume EGCG in higher than normal quantities. Your
doctor should test your liver function regularly in order to determine if EGCG
is an appropriate option for you.
Grab a cup, let it steep, and RELAX!
The Top 8
Benefits of Curcumin
Curcumin is derived from the rhizomes of the curcuma longa linn plant,
a member of the ginger family (zingiberaceae). Curcumin, the active ingredient
in turmeric, aids in management of oxidative stress, inflammatory conditions,
metabolism, arthritis, anxiety, and even hyperlipidemia. Curcumin can be
instrumental in helping to decrease exercise induced inflammation and muscle
soreness, enhancing recovery and performance.
acts as a transcription agent to turn on genes that have been mistakenly
silenced and can even activate p53, the tumor suppressor gene, which can keep
cancer cells at bay.
The Top 8 Benefits
potent anti-inflammatory properties.
decrease your risk of cancer.
reduce your risk of heart disease
relieve arthritis pain.
It can help
decrease your cholesterol
assist in preventing alzheimer's
It can help
in the prevention and management of diabetes
It can help
increase your immunity
It is a
It works on many pathways in the body to
with supplementing curcumin is that it is not very bioavailable alone. Here at
IRM we carry the most bioavailable oral preparation of Curcumin, called
UltraCur, and we even have Curcumin available in IV form! The IV form is an
absolute game changer, as this amazing anti-inflammatory powerhouse can now be
delivered straight into your bloodstream!
The Benefits of Taking NAD+
NAD+ is an essential coenzyme that we cant live without. It is
present in the mitochondria of each cell and declines 50% by age 40-60. The
mitochondria are known as the powerhouse of the cell and make ATP or energy
within the cell. Without sufficient NAD+ our mitochondria struggle to make
sufficient energy, which can be very taxing to our vital organs. Replenishing
NAD+ stores can lead to improved athletic performance, slow the process of
aging, and revitalize our hard working organs. NAD+ plays a key role in
metabolism and DNA repair, which is very important in the prevention of chronic
illnesses and even cancer. The organs with the highest concentrations of NAD+
are the heart and brain, so the lack of NAD+ can put these organs at risk for
degenerative conditions (ie. Alzheimers). For this reason, NAD+ can potentially
be very effective in preventing dementia, Parkinsons, and even multiple
sclerosis. NAD+ is given via intravenous infusion and takes about two to four
hours and depends on each patients tolerance of the drip. During the drip, some symptoms that most
people experience are chest tightness and/or butterflies in their stomach, but
everyone is different. These symptoms are completely benign, and will go away
within 20 seconds of stopping the drip. We like to think of the sensation of
these symptoms as our cells getting the boost of energy that they'd been
working so hard for! Typically, our areas of issue or disease are the areas of
the body in which NAD+ is lacking, thus we typically feel the symptoms in those
areas. In short, you'll feel it where you need it!
At The Institute, we offer the most comprehensive NAD+ protocol to
give you the boost that you need without any baggage. This baggage that I speak
of may come in the form of homocysteine production and senescence, both of
which we are able to prevent here at the institute. Prior to the infusion, we
supply each patient with a supplement called Trimethylglycine (TMG), which
provides the body with methyl and assists in the tolerance of the infusion.
Further, the methyl provided by the TMG prevents the production of
homocysteine, an amino acid that can cause damage to the arteries, during the
NAD+ infusion. This homocysteine, if produced even after TMG supplementation,
can be broken down by Vitamin B6. For this reason, we end each NAD+ IV with an
IV push of Vitamin B6. As far as senescence is concerned, NAD+ has the tendency
to help our cells thrive and get stronger, even the scenecent ones. Senescent
cells are those cells that should've died, but are continuing to live on and
secreting things like inflammatory proteins. To prevent these cells from living
on, we supplement quercetin with our NAD+ treatments as a senolytic. This
allows the NAD+ to boost up the healthy cells and the senescent cells to die
off as they should. Lastly, we finish the infusion with a supplement called
SAMe. This helps to potentiate the effects of the NAD+ infusion and helps you
to feel more energized for even longer. We are currently one of the only
clinics comprehensively taking care of all of the baggage that comes with an
NAD+ infusion, and leaving you to only receive the amazing benefits!
The Most Exciting
Anti-Aging Antioxidant: Resveratrol
Resveratrol is a plant compound that is an excellent antioxidant. Plants actually
produce resveratrol in times of distress caused by a bacteria, virus or fungi
because it can help fight off these pathogens. Along with being an antioxidant,
resveratrol also has anticancer and neuroprotective properties. For years,
resveratrol has been used to treat infectious and inflammatory conditions, but
its most notable benefit is its cardioprotective properties. Resveratrol can
lower blood pressure, by increasing the production of nitric oxide in the body.
This is important because nitric oxide actually relaxes the blood vessels,
decreasing blood pressure, and decreasing the workload on the heart.
Furthermore, resveratrol can help lower body weight, total and LDL or bad
cholesterol, and increase HDL or good cholesterol. Resveratrol can also
increase insulin sensitivity, by activating the AMPK pathway (the same pathway
activated by the diabetes drug Metformin), therefore decreasing the risk of
developing type 2 diabetes. Lastly, resveratrol can ease joint pain by
preventing the breakdown of cartilage in the joints and possibly stopping
osteoarthritis in its tracks. For these reasons, in many animal studies,
resveratrol has been shown to lengthen lifespan.
Resveratrol is found in many plant foods, especially the skin of
grapes, blueberries, raspberries, mulberries, and peanuts. So, consider reading
this a sign to have a glass of wine tonight, you know, for the health benefits.
One of the biggest issues with supplementation of resveratrol is its
poor bioavailability. For this reason, we have an IV preparation of resveratrol
at IRM that will be delivered directly into the bloodstream for maximum
Similarly to resveratrol, pterostilbene is an antioxidant and
antimicrobial compound found in plants. Pterostilbene also has anticancer,
anti-inflammatory, anti-diabetic, and vascular protective properties.
Resveratrol may be superior for its cardioprotective effects, but
pterostilbenes anti-inflammatory and anticancer effects are far superior.
Pterostilbene has strong neuroprotective effects and has been shown to increase
cognitive abilities as well as slow down the process of aging by promoting DNA
repair! Furthermore, pterostilbene stimulates the AMPK pathway, increasing
insulin sensitivity and preventing the onset of type 2 diabetes.
Pterostilbene can be found in blueberries and grapes, but unlike
resveratrol, does not make it through the process of wine making, so you'll
have to eat the grapes to reap the benefits of this compound. Pterostilbene is
also more bioavailable than resveratrol, making it more easily absorbed orally.
Feel Young Again
What is CoQ10? CoQ10 or (coenzyme Q10) is
a fat-soluble nutrient that helps us produce energy, and is found naturally in
the body. Unfortunately, as we age, our bodies produce less and less CoQ10.
Lower levels of CoQ10 can lead to muscle weakness and fatigue, higher blood
pressures, and slowed thinking.
CoQ10 has been found to help with symptoms of
heart failure by restoring optimal levels of energy production. This increased
energy production has been linked with alleviating and even preventing
migraines, and is great for overall brain function. Along with improved
mitochondrial function, CoQ10s antioxidant properties can help protect skin
cells to make it look younger when applied directly.
Individuals may be deficient in CoQ10 if they
suffer from health conditions like heart disease, brain disorders, diabetes or
cancer, due to the increased demands by the respective tissues. Certain
medications like antidepressants, psychotherapeutics, and meds used to treat
heart disease are known to decrease levels of CoQ10.
You can find CoQ10 in a lot of foods that we
eat in our diets. However, most dietary sources have far less amounts of CoQ10
than when given as a supplement. Some of these foods include meats of all
forms, especially organ meats (liver, heart, etc.) and fatty fish. Soybeans,
nuts and seeds, and a variety of vegetables (especially broccoli) also contain
this vital nutrient.
CoQ10 has been known to lower blood sugar and
blood pressure, so individuals who are sensitive to this should take precaution
with CoQ10 supplementation. As always, consult your doctor if you're
considering taking CoQ10.